Medicine in evolution








- Abstract -

Aim and objectives: The present study tries to demonstrate a possible correlation between hs-CRP, LDL cholesterol and cardiovascular risk at patients with coronary angiography revealing significant coronary arthery disease.

Methods: We included in our retrospective study a number of 87 patients with coronary artery disease. There was made a clinical evaluation; EKG, echocardiography, fasting glucose, total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides and hs-CRP were determined. Based on LDL-cholesterol and hs-CRP level we formed 4 groups: group A (LDL-cholesterol>70mg% and hs-CRP>2mg/l; group B (LDL-cholesterol <70mg% and hs-CRP<2mg/l), group C(LDL-cholesterol>70mg% and hs-CRP<2mg/l) and group D(LDL-cholesterol <70mg% and hs-CRP<2mg/l).

Results: There were reported 5 cardiovascular events. The percent of cardiovascular events reported was 10% for group A, 7.62% for group B, 7.14% for group C and 4% for group D.

Conclusions: CRP was a strong predictor of cardiovascular events even in case of patients with normal LDL-cholesterol levels. There is a strong correlation between hs-CRP and LDL-cholesterol level on the hand and the cardiovascular events on the other hand.

Key words: coronary artery disease, hs-CRP, LDL-cholesterol, secondary prevention.




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